Note: You can select multiple files as you normally do in Windows using the CTRL and SHIFT keys.Overview of Configure Boot-Time Defragmentation window
On the Custom tab, you can designate the files that you want to be defragmented at boot-time.
To designate Windows system files for defragmentation, use the System Files tab.
Click Add file(s). The Add Boot-time Defrag Item window opens.
Click Browse to open a standard Browse window. You can select multiple files as you normally do in Windows, using the CTRL and SHIFT keys. Navigate to the desired file and click OK.
Repeat step 2 for every file you want to add. If you change your mind about adding a file, select it and click Remove.
To set the frequency of the defragmentation, select one or more files, click Options, and then select one of these two options from the menu:
Defrag selected at each restart. The selected file or files will be defragmented every time you start or restart your computer. This option is recommended for frequently used files.
Defrag selected on next restart only. The selected file or files will be defragmented the next time your start or restart your computer. This sets up the boot-time defragmentation for one use.
Note: You can select multiple files as you normally do in Windows using the CTRL and SHIFT keys.
When you are finished making your selections, click OK to close the Add Boot-time Defrag Item window.
Note: The final screen of the Defragment Hard Drives wizard also allows you to designate files for boot-time defragmentation. If you added any files through that wizard, they will display here and will be defragmented at boot-time once. You can change settings for these files as described below.
You can designate the files you want to work with in one of several ways:
Click on the rows to select them. You can select multiple files as you normally do in Windows using the CTRL and SHIFT keys.
Make one of the following selections from the Tools menu:
Select all files. Selects all rows.
Invert selection. Where a row is selected , this option clears them; where a row is not selected, this option selects them.
Note: Selecting the check boxes enables the defragmentation; check box selections 
are not synonymous with row selections . See Disable or enable defragmentation below for more information on check box selections.
Defrag selected at each restart. The selected file or files will be defragmented every time you start or restart your computer. This option is recommended for frequently used files.
Defrag selected on next restart only. The selected file or files will be defragmented the next time your start or restart your computer. This sets up the boot-time defragmentation for one use.
To remove an file from boot-time defragmentation and remove it from displaying on the window:
Select the one or more files you want to remove, click Remove and then click Selected item(s).
Click Remove and then All items to remove all the files from the list.
Click Yes on the confirmation window to complete the removal.
By default, all files that you add have their check mark selected , which indicates that the defragmentation is enabled. If you want to disable the defragmentation for a file, but still want to keep it on the list, you can disable the defragmentation.
To enable or disable files, click one of these options from the Tools menu:
Disable selected item(s) or Disable all items. Either disables fragmentation for the files you have selected or disables fragmentation for all files on the window.
Enable selected item(s) or Enable all items. Either enables fragmentation for the files you have selected or enables fragmentation for all files on the window.
Get file properties. Opens a standard Properties window that shows file properties for the selected file.
Open Explorer to file location. Opens a Windows Explorer window, showing the folder that contains the selected file.